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Shape based Monte Carlo code for light transport in complex heterogeneous tissues

机译:基于形状的蒙特卡洛代码,用于复杂异质组织中的光传输

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摘要

A Monte Carlo code for the calculation of light transport in heterogeneous scattering media is presented together with its validation. Triangle meshes are used to define the interfaces between different materials, in contrast with techniques based on individual volume elements. This approach allows to address realistic problems in a flexible way. A hierarchical spatial organisation enables a fast photon-surface intersection test. The application of the new environment to evaluate the impact of the trabecular structure of bone on its optical properties is demonstrated. A model of the trabecular micro structure recovered from microCT data was used to compute light distribution within tissue. Time-resolved curves across a spherical bone volume were computed. The work presented enables simulation of radiative transport in complex reality-based models of tissue and serves as a powerful, generic tool to study the effect of heterogeneity in the field of biomedical optics.
机译:提出了用于计算非均质散射介质中光传输的蒙特卡洛代码及其验证。与基于单个体积元素的技术相比,三角形网格用于定义不同材料之间的界面。这种方法可以灵活解决实际问题。分层的空间组织可以进行快速的光子-表面相交测试。演示了在新环境中评估骨小梁结构对其光学特性的影响的应用。从microCT数据恢复的小梁微结构模型用于计算组织内的光分布。计算了跨球形骨体积的时间分辨曲线。提出的工作能够在复杂的基于现实的组织模型中模拟辐射传输,并用作研究生物医学光学领域中异质性影响的强大通用工具。

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